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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PITPNB
All Species:
42.12
Human Site:
T250
Identified Species:
92.67
UniProt:
P48739
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48739
NP_036531.1
271
31540
T250
I
R
R
M
E
D
E
T
Q
K
E
L
E
T
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101197
272
31620
T250
I
R
R
M
E
D
E
T
Q
K
E
L
E
T
L
Dog
Lupus familis
XP_851991
272
31647
T250
I
R
R
M
E
D
E
T
Q
K
E
L
E
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P53811
271
31468
T250
I
R
R
M
E
D
E
T
Q
K
E
L
E
T
M
Rat
Rattus norvegicus
P53812
271
31431
T250
I
R
R
M
E
D
E
T
Q
K
E
L
E
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508779
330
37294
T309
I
R
R
M
E
D
E
T
Q
K
E
L
E
A
M
Chicken
Gallus gallus
NP_001034355
272
31702
T250
I
R
R
M
E
D
E
T
Q
K
E
L
E
A
L
Frog
Xenopus laevis
NP_001086964
271
31542
T250
I
R
R
M
E
D
K
T
Q
R
E
L
E
A
M
Zebra Danio
Brachydanio rerio
NP_957214
272
31754
T250
I
R
R
M
E
E
E
T
Q
R
E
L
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524404
272
31268
T251
I
R
A
I
E
D
Q
T
K
E
E
L
D
K
A
Honey Bee
Apis mellifera
XP_624564
271
31530
T251
I
R
A
I
E
E
S
T
K
E
E
L
D
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
97.4
N.A.
97.4
97.7
N.A.
76
91.1
87.8
84.1
N.A.
63.9
61.6
N.A.
N.A.
Protein Similarity:
100
N.A.
98.5
98.5
N.A.
98.5
98.8
N.A.
80.3
94.4
94.8
91.1
N.A.
76.8
76.7
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
100
100
N.A.
93.3
86.6
80
73.3
N.A.
46.6
40
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
80
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
0
0
0
0
0
0
28
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
82
0
0
0
0
0
0
19
0
0
% D
% Glu:
0
0
0
0
100
19
73
0
0
19
100
0
82
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
19
64
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
37
% L
% Met:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
46
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
82
0
0
0
0
0
10
% Q
% Arg:
0
100
82
0
0
0
0
0
0
19
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
46
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _